"Earth scientists long believed that humans were insignificant in comparison with the vastness of geological time and the power of geophysical forces. For this reason, many were reluctant to accept that humans had become a force of nature, and it took decades for the present understanding to be achieved. Those few who refuse to accept it are not ignorant, but they are stubborn. They are not unintelligent, but they are stuck on details that cloud the larger issue. Scientific communities include tortoises and hares, mavericks and mules. "
One of the greatest scientist of all time, Isaac Newton, warned against this tendency more than three centuries ago. Writing in "Principia Mathematica" in 1687, he noted that once scientists had successfully drawn conclusions by "general induction from phenomena," then those conclusions had to be held as "accurately or very nearly true notwithstanding any contrary hypothesis that may be imagined…. "
Climate-change deniers can imagine all the hypotheses they like, but it will not change the facts nor "the general induction from the phenomena."
None of this is to say that there are no uncertainties left — there are always uncertainties in any live science. Agreeing about the reality and causes of current global warming is not the same as agreeing about what will happen in the future. There is continuing debate in the scientific community over the likely rate of future change: not "whether" but "how much" and "how soon." And this is precisely why we need to act today: because the longer we wait, the worse the problem will become, and the harder it will be to solve.