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Oct 28, 2020

COVID's cognitive costs? Some patients' brains may age 10 years

(REUTERS) A non-peer-reviewed study of more than 84,000 people, led by Adam Hampshire, a doctor at Imperial College London, found that in some severe cases, coronavirus infection is linked to substantial cognitive deficits for months.

"Our analyses ... align with the view that there are chronic cognitive consequences of having COVID-19," the researchers wrote in a report of their findings. "People who had recovered, including those no longer reporting symptoms, exhibited significant cognitive deficits."

Cognitive tests measure how well the brain performs tasks - such as remembering words or joining dots on a puzzle. Such tests are widely used to assess brain performance in diseases like Alzheimer's, and can also help doctors assess temporary brain impairments.

Hampshire's team analysed results from 84,285 people who completed a study called the Great British Intelligence Test. The findings, which have yet to be reviewed by other experts, were published online on the MedRxiv website.

The cognitive deficits were "of substantial effect size", particularly among people who had been hospitalised with COVID-19, the researchers said, with the worst cases showing impacts "equivalent to the average 10-year decline in global performance between the ages of 20 to 70".

Scientists not directly involved with the study, however, said its results should be viewed with some caution.

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