Nature - Subnanometre single-molecule localization, registration and distance measurements Steven Chu and his co-authors Chu's method involves using two different colored lights, beams of tiny light and other techniques (feedback control etc...) to reduce the signal-to-noise ratio in optical microscopes... The improved resolution will allow the structure of large, multisubunit biological complexes in biologically relevant environments to be deciphered at the single-molecule level.
Please read on at NextBigFuture
Please read on at NextBigFuture
