Dec 1, 2011

Early sign of Alzheimer's reversed in lab - ScienceDaily

One of the earliest known impairments caused by Alzheimer's disease -- loss of sense of smell -- can be restored by removing a plaque-forming protein in a mouse model of the disease, a study led by a Case Western Reserve University School of Medicine researcher finds.

The study confirms that the protein, called amyloid beta, causes the loss.
"The evidence indicates we can use the sense of smell to determine if someone may get Alzheimer's disease, and use changes in sense of smell to begin treatments, instead of waiting until someone has issues learning and remembering," said Daniel Wesson, assistant professor of neuroscience at Case Western Reserve and lead investigator. "We can also use smell to see if therapies are working."