British Medical Journal - Timing of onset of cognitive decline: results from Whitehall II prospective cohort study University College London researchers found a 3.6% decline in mental reasoning in women and men aged 45-49.
Decline in cognitive test scores over 10 years (% change=change/range of text×100) as function of baseline age cohort in men and women, estimated from linear mixed models. P values denote test for linear trend across age categories, derived by entering them as continuous variable
Tests of memory, reasoning, vocabulary, and phonemic and semantic fluency, assessed three times over 10 years.
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