Jan 25, 2013

Researchers discover new mutations driving malignant melanoma

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously found.

Reporting their findings in the Jan. 24 issue of Science Express, the researchers from Dana-Farber Cancer Institute and the Broad Institute said the highly "recurrent" mutations – occurring in the tumors of many people – may be the most common mutations in melanoma cells found to date.

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